Cell Biology

General

• Code: TΑBO-11-A1
• Semester: 1st
• Study Level: Undergraduate
• Course type: General Background
• Teaching and exams language: Greek (English for Erasmus students)
• The course is offered to Erasmus students
• Teaching Methods (Hours/Week): Tutorials (Theory) (2) / Practice Works (2)
• ECTS Units: 5
• Course homepage: https://eclass.emt.ihu.gr/courses/FD318/
• Instructors: Alatzas Anastasios, Papadopoulos Nikolaos
• Class Schedule:
  • Thu 12:00 - 14:00: Θεωρία, Αίθουσα Αγγλικών
  • Thu 14:00 - 16:00: Εργαστήριο, Αίθουσα Αγγλικών - Ομάδα Α
  • Thu 16:00 - 18:00: Εργαστήριο, Αίθουσα Αγγλικών - Ομάδα Β

Course Contents

• The cellular nature of life: Living organisms. Cellasthebasicunitoflife. Prokaryotes and eukaryotes. Animal and plant cell.
• Organic macromolecules: Carbohydrates, lipids, proteins, nucleic acids. Structure and function of macromolecules.
• Transport in and out of the cell: Structure of cellular membranes. Water movement through cell membranes. Diffusion and osmosis. Liquid mosaic model. Cell communication.
• Cell and subcellular organelles: Nucleus. Chloroplasts and plastids. Mitochondria. Ribosomes. Peroxisomes. Vacuoles. ER. Golgi apparatus. Cytoskeleton. Cell wall.
• Energy and the cell: Enzymes and metabolism. Cofactors. Enzyme regulation. The ATP molecule. Metabolic pathways.
• Respiration: Glucose oxidation. Glucolysis. Aerobic respiration. Citric acid cycle. Oxidative phosphorylation. Non-aerobic respiration.
• Photosynthesis: The nature of light. Photosynthetic pigments. Light and dark reactions of photosynthesis. Photosystems, cyclic phosphorylation, ATP synthesis, Calvin cycle, C3, C4 and CAM plants. Photorespiration.
• Cell cycle and cell division: Eukaryotic chromosome. Mitosis. Meiosis and homologous recombination. Genes and heredity.
• Gene expression: DNA structure and replication. DNA transcription and mRNA maturation. Genetic code. Protein synthesis.

Educational Goals

With the successful completion of the course the student will:

• know the cellular structure of living organisms,
• comprehend the structure and function of macromolecules,
• know the basic principles of cellular metabolism,
• know the stages of photosynthesis,
• know the stages of cell division,
• know the basic functions concerning genetic information- storage, replication and expression,
• comprehend the basic methods of cellular biology,
• know how to use the optical microscope.

General Skills

• Adapting to new situations.
• Decision-making.
• Working independently.
• Team work.
• Production of new research ideas.
• Respect for the natural environment.
• Production of free, creative and inductive thinking.
• Working in an interdisciplinary environment.

Teaching Methods

• Face-to-face.

Use of ICT means

• Use of ICT in both lecturesand laboratory education.
• Use of e-class platform for educational activities and  communication with students.

Teaching Organization

Students Evaluation

Final written examination including:

• multiple choice questionnaires,
• short-answer questions,
• open-ended questions.

Recommended Bibliography

1. Βιολογία των Φυτών, Raven Peter, Ray F. Evert, Susan E. Eichhorn.
2. Μοριακή Κυτταρική Βιολογία, Harvey Lodish, Arnold Berk, Chris Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelica Amon, Kelsey Martin.
3. Βασικές Αρχές Κυτταρικής Βιολογίας 4ηέκδοση, Alberts B., Bray D., Hopkin K., Johnson A., Lewis J., Raff M., Roberts K., Walter P.
4. Μοριακή Βιολογία του Κυττάρου, Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter, John Wilson, Tim Hunt.
5. Βιολογία κυττάρου, Μαργαρίτης Λουκάς Χ.
6. Μοριακες δομες και βιοχημικες διεργασιες κατα την εξελιξη των οργανισμων, Ιωαννης Γουναρης.
7. Το Κύτταρο, Geoffrey M. Cooper.