Nanobiotechnology and Biosensors

General

• Code: ΤΑΒΟ-96-Θ6
• Semester: 9th
• Study Level: Undergraduate
• Course type: Skills Development
• Teaching and exams language: Greek (English for Erasmus students)
• The course is offered to Erasmus students
• Teaching Methods (Hours/Week): Lectures (3)
• ECTS Units: 4
• Class Schedule:
  • Fri 15:00 - 18:00:

Course Contents

• Historical development of biosensors.
• Basic concepts of nanotechnology.
• Elements of electrochemistry.
• Cyclic voltammetry, voltammetry and chronoamperometry.
• Electrochemical impedance spectroscopy.
• Optical biosensors.
• Cellular biosensors.
• Biomolecule immobilization methods.
• Microelectromechanical Systems (MEMS) – Introduction to Micromechanics. Commercial applications.
• Basic Technologies of Micromechanics: Lithography. Etching (Wet, Dry). Surface micromechanics. Volume micromechanics.

Educational Goals

The course is the basic introduction to the scientific field of biosensors and nanotechnology and their application in the life sciences, as well as all the individual techniques and methods used for their development, study and application in modern analytical and diagnostic science, food safety and environment.
The course material aims to introduce students to the basic concepts of Nanotechnology, Biosensors, Electrochemistry and Micromechanics, covering a very broad field of complementary knowledge, with extensive elements of microfluidics, photonics, biomolecular processes, molecular recognition, analytical chemistry and quality control.
It also refers to introductory concepts and methodologies for designing and prototyping microelectromechanical systems and biosensors, conducting analyzes with high-throughput systems, using expert systems, knowledge of microelectromechanical system materials (silicon, polymer materials, etc.). and the basics micromechanical technologies (lithography, etc.).
Finally, the aim of the course is the students’ understanding of the importance of biosensors and nanotechnology in modern analytical and diagnostic science and the individual contribution to the manufacturing sector, industry and services, while at the same time contributing to the perspective of distinct professional employment specializing in analytical processes with advanced methods.

Upon successful completion of the course, the student will be able to:

• Has an understanding of the basic principles of biosensors and nanotechnology, related technologies and their fields of application.
• Has knowledge of Micromechanics tools and techniques and analysis based on different biosensor systems.
• Is able to design basic micromechanical devices.
• Is able to conduct laboratory analyzes using at least two different types of biosensors.
• Uses his knowledge to search for new technologies and exploit research results in the design of innovative biosensor analysis systems.
• Collaborates with fellow students to create and present a plan to apply nanotechnology and biosensing approaches to a real-world application/analytical need of their choice, while possessing skills in written and oral communication of project results.

General Skills

• Autonomous Work.
• Work in an interdisciplinary environment.
• Generation of new research ideas.
•  Promotion of free, creative and inductive thinking.

Teaching Methods

• In the classroom, face to face.

Use of ICT means

• Basic software (windows, word, power point, the web, etc.).
• Support of learning process through the electronic platform / e-class.

Teaching Organization

Students Evaluation

• Final written exam in the theory of the course (50%).
• Essay  (50%).

Recommended Bibliography

1. Μ. Προδρομίδης,ΗλεκτροχημικοίΑισθητήρες &Βιοαισθητήρες,2010.
2. F.S. Ligler, Optical Biosensors: Present & Future, Elsevier 2002.
3. J.Y.Yoon, Introduction to Biosensors: From Electric Circuits to Immunosensors, Springer 2012.
4. J. Li, N. Wu,Biosensors Based on Nanomaterials and Nanodevices (Nanomaterials and their Applications), CRC 2013.

Related Research Journals

1. Biosensors and Bioelectronics.
2. Sensors & Actuators.